Although there are no reports of toxicity for ground virgin's bower
specifically, it is known that many - and probably all - members of the genus Clematis
are mildly poisonous to humans and animals. There are two main toxins in the ground virgin's bower
; ranunculin and glycosides, and these can be found in all parts of the plant
. The ranunculin causes severe pain and blistering in the mouth if the plant
is ingested, while the glycosides affect the cardiac system. Other symptoms include a burning sensation in the mouth, excess salivation and vomiting. When the ground virgin's bower
is extensively handled, it causes skin redness, along with a burning sensation in the skin, but this is usually minor and only lasts for a few minutes. Due to its unpleasant taste and aggressive reaction with skin and mucosa, cases of poisoning are very rare.