The Santalum genus is generally adaptable to different soils, but well-drained loamy soil is ideal. It prefers full sun to partial shade and moderate watering. To plant, prepare the soil with organic matter, position the plant, and water thoroughly. Regular monitoring for pests and diseases is essential, as Santalum has a few common threats. Ensure to tailor these guidelines to the specific Santalum species, as their needs may slightly differ.