Cyphostemma are succulent plants requiring a well-drained soil mix, bright light, and a warm environment to thrive. Basic care includes moderate watering, allowing the soil to dry out between sessions, and ensuring high temperatures particularly in the growing season. Common challenges involve overwatering, which can lead to root rot, and pests such as spider mites. Seasonal considerations consist of reduced watering in winter and protection from cold temperatures, while increasing watering frequency during the active growth period in spring and summer.