Periploca, a genus of climbing plants, needs a warm climate, moderately watered soil, and partial to full sun exposure for optimum growth. The plants are adept at surviving in slightly alkaline to neutral soil. They can face challenges like root rot due to excessive water, aphid infestation, and susceptibility to fungal diseases. Seasonal considerations for periploca include higher watering needs in summer, protection against frost in winter, and regular pruning in the spring to encourage fresh growth.