Mayapple, a genus of deciduous rhizomatous herbs, thrives in shady conditions with well-draining humus-rich soil and steady moisture. It prefers cool temperatures, and adequate mulching is pivotal in summer to keep roots moist and cool. Care should be taken against common challenges like root rot, fungal diseases, and particular pests like slugs, weevils, and deer. Most varieties are hardy, but the plant's foliage may die back in extreme cold. Seasonal care includes reduced watering in winter and careful attention to light during growing seasons.